In Germany, it’s recommended a natural extract from the herb butterbur (Petasites hybridus) to maintain head cavity comfort.1-3 In clinical trials in both Germany and the United States, butterbur reduced the incidence of head cavity discomforts by approximately 61%.1-2
Butterbur’s principal active constituent, petasin, reduces smooth muscle spasms and helps relax the constriction of cerebral blood vessels. Butterbur’s ability to relax constricted arteries and smooth muscle may help control head cavity discomfort.
Migra-Eeze™ contains butterbur root extract standardized to provide 22.5 mg of petasins with each daily dose of two softgels. Riboflavin (vitamin B2) and ginger are included based on the ability of these nutrients to exert functional changes that may also guard against cranial discomfort.
- Neurology. 2004 Dec 28;63(12):2240-4.
- Int J Clin Pharmacol Ther. 2000 Sep;38(9):430-5.
- Am J Health Syst Pharm. 2010 May 1;67(9):705-11